Eif4a antibody

Author: rdqw

August undefined, 2024

WebRabbit polyclonal antibody to EIF4A1: Alternative names: DDX2A, EIF4A, Eukaryotic initiation factor 4A-I, eIF-4A-I, eIF4A-I, ATP-dependent RNA helicase eIF4A-1 (click to expand) Expiration Date: 12 months from date of receipt. Note: … WebRabbit polyclonal antibody to EIF4A1: Alternative names: anti-eIF-4A-I antibody, anti-eIF4A-I antibody, anti-ATP-dependent RNA helicase eIF4A-1 antibody, anti-EIF4A1 antibody, anti-DDX2A antibody, anti-EIF4A antibody (click to expand) Expiration Date: 12 months from date of receipt. Note: For research use only.

eIF4A1 Recombinant Polyclonal Antibody (711505)

WebeIF4A1 Polyclonal Antibody, Invitrogen™-Rabbit Polyclonal Antibody Shop eIF4A1 Polyclonal Antibody, Invitrogen™ at Fishersci.co.uk English ... DDX2A, EIF-4A, EIF4A, eIF-4A-I, eIF4A-I, ATP-dependent RNA helicase eIF4A-1, eukaryotic initiation factor 4A-I, eukaryotic initiation factor 4AI, eukaryotic translation initiation factor 4A ... WebNov 19, 2006 · Furthermore, eIF4A physically associates with Mad and Medea, and promotes their degradation following activation of Dpp signalling in a translation-independent manner. ... The primary antibodies ... tarves road pitmedden

eIF4A (F52) Antibody Cell Signaling Technology

WebThe antibody is from purified rabbit serum by affinity purification via sequential chromatography on phospho-peptide and non-phospho-peptide affinity columns. 保存: ... Inhibits the helicase activity of EIF4A. Modulates the activation of JUN kinase. Down-regulates the expression of MAP4K1, thus inhibiting events important in driving invasion ... WebFeb 13, 2024 · The finding of eIF4A and eIF4G in stress granules suggests that they do not participate in mRNA translation. Human HAP1 cells depleted for eIF2A, eIF2D, or both factors, were able to synthesize luciferase from an mRNA bearing the HCV IRES even when eIF2α was phosphorylated. WebAntibodies that detect eIF4A2 can be used in several scientific applications, including Western Blot, Immunohistochemistry, Immunocytochemistry, ELISA and Peptide array. … tarvia construction

Novel eIF4A1 inhibitors with anti‐tumor activity in lymphoma

Anti-eIF4A1 antibody (ab31217) Abcam

WebeIF4F binds 7-methylguanylate at the 5′ end of mRNA, thereby modulating protein translation. eIF4A carries out scanning and unwinds the secondary structures of several mRNAs at the 5′ untranslated region (5′-UTR), thus … WebeIF4AI/II Antibody (H-5) is a monoclonal anti-eIF4AI/II antibody that is recommended for WB, IP, IF, IHC(P) and ELISA. Cited in 12 publications ... eIF4A, eIF3 and the 40S ribosome. Human eIF4AI (eIF4A, DDX2A) is a 406 amino acid protein that is 92.7% homologous to mouse eIF4AI. The promoter region of human eIF4A1 contains TATA and CAAT motifs ... tarves cupWebJun 14, 2024 · The “cap-binding complex” eukaryotic initiation factor 4F (eIF4F) is one of the major components for translation initiation. eIF4A, as an ATP-dependent RNA helicase that forms the enzymatic core... tarvia seal syracuse

"WebOct 2, 2014 · While several eIF4A-regulated genes have been identified, in-depth studies have yet to provide a genome-wide description of the eIF4A target gene landscape. We sought to comprehensively define the cellular mRNAs regulated by eIF4A and investigate the mRNA features that confer dependence on this helicase by directly blocking its activity. " - Eif4a antibody

Eif4a antibody

Chaperone Hsp27 inhibits translation during heat shock by binding …

WebAnti-eIF4A2 antibody See all eIF4A2 primary antibodies Description Rabbit polyclonal to eIF4A2 Host species Rabbit Tested applications Suitable for: … WebSep 4, 2024 · Eukaryotic translation initiation factor (eIF) 4A plays an essential role in translation initiation by unwinding the secondary structure of messenger RNA (mRNA) upstream of the start codon, enabling active ribosomal recruitment on …

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WebJun 14, 2024 · Antibodies for eIF4A (#2013) and HSF1 (#4356) were obtained from Cell Signaling Technology (Danvers, MA, USA). Phosphorylated HSF1 (Ser 326) antibody … WebEukaryotic initiation factor 4E (eIF4E) binds to the mRNA cap structure to mediate the initiation of translation (1,2). eIF4E interacts with eIF4G, a scaffold protein that promotes assembly of eIF4E and eIF4A into the eIF4F complex (2). eIF4B is thought to assist the eIF4F complex in translation initiation. Upon activation by mitogenic and/or ...

WebWe demonstrate that chaperone Hsp27 is a heat shock-induced inhibitor of cellular protein synthesis. Translation of most mRNAs requires formation of a cap-binding initiation complex known as eIF4F, consisting of factors eIF4E, eIF4A, eIF4E kinase Mnk1, poly(A)-binding protein, and adaptor protein eIF4G. WebeIF4A (F52) Antibody detects endogenous levels of total eIF4A1, eIF4A2 and eIF4A3 proteins. Species Reactivity: Human, Mouse, Rat, Monkey Source / Purification Polyclonal …

WebeIF4A (C32B4) Rabbit mAb detects endogenous levels of total eIF4A protein. Species Reactivity: Human, Mouse, Rat, Monkey Source / Purification Monoclonal antibody is … WebHuman eIF4A2 interacts with the NS5B protein of Hepatitis C virus (HCV) and facilitates the genomic RNA synthesis of NS5B protein by unwinding the secondary structure of the HCV genome. It is ubiquitously expressed in most of normal tissues, but in variable amounts. For Research Use Only. Not for use in diagnostic procedures.

WebeIF4A is the canonical DEAD box RNA-stimulated ATPase and helicase that facilitates translation initiation by unwinding long and complex 5′ untranslated region secondary structures common to many eukaryotic mRNAs ( Rogers et al., 2002; Tuteja et al., 2008; Parsyan et al., 2011; Andreou and Klostermeier, 2013; Linder and Fuller-Pace, 2013; …

WebOct 29, 2024 · Thus, eIF4A inhibitors, in development as anticancer drugs, may also act as cancer immunotherapies. ... where it translated into clinical benefit with the use of anti-CTLA4 antibody (ipilimumab) 1 ... the bridgeway cinemaWebInvitrogen Anti-eIF4A1 Recombinant Polyclonal, Catalog # 711505. Tested in Western Blot (WB), Immunocytochemistry (ICC/IF) and Flow Cytometry (Flow) applications. This … tarvia seal corporationWebEukaryotic initiation factor 4A (EIF4A) has an essential role in the binding of mRNA to the 43S preinitiation complex when protein synthesis begins, as EIF4A unwinds RNA … the bridge waverly new yorkWebThe exact population can be produced in every lot, circumventing the biological variability typically associated with polyclonal antibody production. Target Information eIF4A2 is a 407 amino acid ATP-dependent RNA helicase belonging to the DEAD box helicase family. the bridge wayfarer bagWebAnti-eIF4A1 antibody [EPR14506] (ab185946) Research with confidence – consistent and reproducible results with every batch. Long-term and … tarvey topWebMar 21, 2024 · eIF4F is a multi-subunit complex, the composition of which varies with external and internal environmental conditions. It is composed of at least EIF4A, EIF4E … the bridgeway behavioral healthWebFeb 24, 2024 · eIF4AIII Antibody (B-2) is an IgG 2b κ mouse monoclonal eIF4AIII antibody (also designated EIF4A3 antibody) suitable for the detection of the eIF4AIII protein of … tarves holiday cottages